N6-methyladenosine-related microRNAs risk model trumps the isocitrate dehydrogenase mutation status as a predictive biomarker for the prognosis and immunotherapy in lower grade gliomas

• Main Authors: Feng Yuan (Author), Yingshuai Wang (Author), Xiangming Cai (Author), Chaonan Du (Author), Junhao Zhu (Author), Chao Tang (Author), Jin Yang (Author), Chiyuan Ma (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Lower grade gliomas [LGGs; World Health Organization (WHO) grades 2 and 3], owing to the heterogeneity of their clinical behavior, present a therapeutic challenge to neurosurgeons. The aim of this study was to explore the N6-methyladenosine (m6A) modification landscape in the LGGs and to develo...