Possible Role of Interleukin-6 in PC12 Cell Death Induced by MPP+ and Tetrahydroisoquinoline

• Main Authors: Naoko Shimma (Author), Nobuteru Akiyama (Author), Michiko Umezawa (Author), Yasunobu Okuma (Author), Yasuyuki Nomura (Author), Takeshi Saito (Author), Syunji Horie (Author), Toshihiko Murayama (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Interleukin (IL)-6 has been shown to protect neuronal cells from cell death induced by various stimulants. Although neuronal cells including PC12 cells were shown to produce IL-6, little is known about the effects of dopaminergic neurotoxins, 1,2,3,4-tetrahydroisoquinoline (TIQ) and 1-meth...