Solid lipid nanoparticle as an effective drug delivery system of a novel curcumin derivative: formulation, release in vitro and pharmacokinetics in vivo

• Main Authors: Wenmei Zhao (Author), Mingtang Zeng (Author), Ke Li (Author), Chao Pi (Author), Zerong Liu (Author), Chenglin Zhan (Author), Jiyuan Yuan (Author), Zhilian Su (Author), Yuxun Wei (Author), Jie Wen (Author), Fengjuan Pi (Author), Xinjie Song (Author), Robert J. Lee (Author), Yumeng Wei (Author), Ling Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Curcumin (Cur) has a short duration of action which limits its therapeutic efficacy. Carbonic acid 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 4-[7-(4-hydroxy-3-methoxy-phenyl)-3,5-dioxo-hepta-1,6-dienyl]-2-...