Cleft Palate and Aortic Dilatation as Clues for Loeys-Dietz Syndrome

• Main Authors: Pierluigi Zaza (Author), Flavia Indrio (Author), Annalisa Fracchiolla (Author), Matteo Rinaldi (Author), Giovanni Meliota (Author), Alessia Salatto (Author), Antonio Bonacaro (Author), Gianfranco Maffei (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Loeys-Dietz syndrome (LDS) is a rare autosomal-dominant disorder of the connective tissue with some typical vascular findings, skeletal manifestations, craniofacial features, and cutaneous findings with a wide phenotypic spectrum. Six different genes are involved in LDS and the diagnosis is based on...