Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1,2,4-Triazole

• Main Authors: Shantaram Gajanan Khanage (Author), S. Appala Raju (Author), Popat Baban Mohite (Author), Ramdas Bhanudas Pandhare (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: An efficient method has been described for synthesis of 6-(substituted aryl)-4-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)-1, 6-dihydropyrimidine-2-thiol, as a beneficial antimicrobial, anticonvulsant and anticancer agents. Methods: The clalcones of title compounds were synthesized in three steps...