In Vitro Hepatic Metabolism of Curcumin Diethyl Disuccinate by Liver S9 from Different Animal Species

• Main Authors: Ponsiree Jithavech (Author), Pahweenvaj Ratnatilaka Na Bhuket (Author), Wiwat Supasena (Author), Guanyinsheng Qiu (Author), Shengqing Ye (Author), Jie Wu (Author), Tin Wui Wong (Author), Pornchai Rojsitthisak (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver S9 (LS9) is a nearly complete collection of all hepatic drug-metabolizing enzymes. It is a low-cost model for predicting drug metabolic activity. This study aimed to identify the suitability of using LS9 of different animal sources in drug metabolism profiling with respect to the possible tran...