Transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption

• Main Authors: Mengyi Yan (Author), Xiayun Chen (Author), Xiaotong Li (Author), Qianqian Liu (Author), Baixue Yu (Author), Yi Cen (Author), Wei Zhang (Author), Yibin Liu (Author), Xinxuan Li (Author), Ying Chen (Author), Tao Wang (Author), Shiying Li (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immunosuppressive phenotype of tumor cells extensively attenuates the immune activation effects of traditional treatments. In this work, a transferrin receptor (TfR) targeted immunostimulant (PTI) is fabricated for photodynamic immunotherapy against metastatic tumors by interrupting β-catenin si...