TIM-3 Rs10515746 (A/C) and Rs10053538 (C/A) Gene Polymorphisms and Risk of Multiple Sclerosis

• मुख्य लेखकों: Esmat YAGHOOBI (लेखक), Saeed ABEDIAN (लेखक), Omid BABANI (लेखक), Maryam IZAD (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Tehran University of Medical Sciences, 2016-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) caused by autoreactive T cells against myelin antigens. T-cell immunoglobulin mucin -3 (TIM-3) is a negative regulator glycoprotein expressed by a range of immune cells, including, Th1 cells, activated C...