TIM-3 Rs10515746 (A/C) and Rs10053538 (C/A) Gene Polymorphisms and Risk of Multiple Sclerosis

• Auteurs principaux: Esmat YAGHOOBI (Auteur), Saeed ABEDIAN (Auteur), Omid BABANI (Auteur), Maryam IZAD (Auteur)
• Format: Livre
• Publié: Tehran University of Medical Sciences, 2016-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) caused by autoreactive T cells against myelin antigens. T-cell immunoglobulin mucin -3 (TIM-3) is a negative regulator glycoprotein expressed by a range of immune cells, including, Th1 cells, activated C...