Effects of OPC-51803, a Novel, Nonpeptide Vasopressin V2-Receptor Agonist, on Micturition Frequency in Brattleboro and Aged Rats

• Main Authors: Shigeki Nakamura (Author), Takahiro Hirano (Author), Yoshitaka Yamamura (Author), Shuji Itoh (Author), Kazumi Kondo (Author), Toyoki Mori (Author), Toshimi Kambe (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: We assessed the effects of OPC-51803 ((5R)-2-[1-(2-chloro-4-(1-pyrrolidinyl)benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N-isopropylacetamide), a nonpeptide vasopessin V2-receptor agonist, on micturition frequency in female homozygous Brattleboro rats (strain carries hereditary diabet...