Pharmacogenetics-Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort

• Main Authors: Matias F. Martinez (Author), Enzo Alveal (Author), Tomas G. Soto (Author), Eva I. Bustamante (Author), Fernanda Ávila (Author), Shrikant I. Bangdiwala (Author), Ivonne Flores (Author), Claudia Monterrosa (Author), Ricardo Morales (Author), Nelson M. Varela (Author), Alison E. Fohner (Author), Luis A. Quiñones (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Infections in hematological cancer patients are common and usually life-threatening; avoiding them could decrease morbidity, mortality, and cost. Genes associated with antineoplastics' pharmacokinetics or with the immune/inflammatory response could explain variability in infection...