A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats

• Main Authors: Yu Shen (Author), Bin Zheng (Author), Hao Sun (Author), Songrui Wu (Author), Jiyuan Fan (Author), Jianzu Ding (Author), Meng Gao (Author), Qingming Kong (Author), Di Lou (Author), Haojie Ding (Author), Xunhui Zhuo (Author), Shaohong Lu (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Toxoplasma gondii is an obligate intracellular apicomplexan parasite and is responsible for zoonotic toxoplasmosis. It is essential to develop an effective anti-T. gondii vaccine for the control of toxoplasmosis, and this study is to explore the immunoprotective effects of a live...