The gene mutations and subtelomeric DNA methylation in immunodeficiency, centromeric instability and facial anomalies syndrome

• Váldodahkkit: Haochang Hu (Dahkki), Chujia Chen (Dahkki), Shanping Shi (Dahkki), Bin Li (Dahkki), Shiwei Duan (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2019-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) is a rare autosomal recessive disorder, which is characteristic of a severe impairment of immunity. In the genetic aspect, ICF is featured with mutations primarily located in the specific genes (DNMT3B for ICF1, ZBTB24 for...