The gene mutations and subtelomeric DNA methylation in immunodeficiency, centromeric instability and facial anomalies syndrome

• Những tác giả chính: Haochang Hu (Tác giả), Chujia Chen (Tác giả), Shanping Shi (Tác giả), Bin Li (Tác giả), Shiwei Duan (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2019-08-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) is a rare autosomal recessive disorder, which is characteristic of a severe impairment of immunity. In the genetic aspect, ICF is featured with mutations primarily located in the specific genes (DNMT3B for ICF1, ZBTB24 for...