The gene mutations and subtelomeric DNA methylation in immunodeficiency, centromeric instability and facial anomalies syndrome

• मुख्य लेखकों: Haochang Hu (लेखक), Chujia Chen (लेखक), Shanping Shi (लेखक), Bin Li (लेखक), Shiwei Duan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) is a rare autosomal recessive disorder, which is characteristic of a severe impairment of immunity. In the genetic aspect, ICF is featured with mutations primarily located in the specific genes (DNMT3B for ICF1, ZBTB24 for...