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The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis

Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity. The genetic association of HDMTX has been widely investigated...

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Bibliographic Details
Main Authors:	Zaiwei Song (Author), Yang Hu (Author), Shuang Liu (Author), Dan Jiang (Author), Zhanmiao Yi (Author), Mason M. Benjamin (Author), Rongsheng Zhao (Author)
Format:	Book
Published:	Frontiers Media S.A., 2021-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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