Protective effect of kaempferol glucoside against lipopolysaccharide-caused acute lung injury via targeting Nrf2/NF-κB/NLRP3/GSDMD: Integrating experimental and computational studies

• Autori principali: Wesam H. Abdulaal (Autore), Ulfat M. Omar (Autore), Mustafa Zeyadi (Autore), Dina S. El-Agamy (Autore), Nabil A. Alhakamy (Autore), Naif A. R. Almalki (Autore), Hani Z. Asfour (Autore), Mohammed W. Al-Rabia (Autore), Abdulrahim A. Alzain (Autore), Gamal A. Mohamed (Autore), Sabrin R.M. Ibrahim (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2024-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The current study explored the protective potential of kaempferol 3-sophoroside-7-glucoside (KSG) against acute lung injury (ALI). Pre-treatment with KSG effectively secured mice from ALI and showed similar efficaciousness to dexamethasone. KSG markedly increased the survival rate and alleviated lun...