Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures.

• Main Authors: Anthony A Ruberto (Author), Caitlin Bourke (Author), Amélie Vantaux (Author), Steven P Maher (Author), Aaron Jex (Author), Benoit Witkowski (Author), Georges Snounou (Author), Ivo Mueller (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Plasmodium vivax sporozoites reside in the salivary glands of a mosquito before infecting a human host and causing malaria. Previous transcriptome-wide studies in populations of these parasite forms were limited in their ability to elucidate cell-to-cell variation, the...