Iron accumulation in skeletal muscles of old mice is associated with impaired regeneration after ischaemia-reperfusion damage

• Hoofdauteurs: Francesca M. Alves (Auteur), Kai Kysenius (Auteur), Marissa K. Caldow (Auteur), Justin P. Hardee (Auteur), Peter J. Crouch (Auteur), Scott Ayton (Auteur), Ashley I. Bush (Auteur), Gordon S. Lynch (Auteur), René Koopman (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wiley, 2021-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Oxidative stress is implicated in the insidious loss of muscle mass and strength that occurs with age. However, few studies have investigated the role of iron, which is elevated during ageing, in age‐related muscle wasting and blunted repair after injury. We hypothesized that iro...