Folate-Targeted PEGylated Magnetoliposomes for Hyperthermia-Mediated Controlled Release of Doxorubicin

• Main Authors: Emílio R. Cintra (Author), Tacio G. Hayasaki (Author), Ailton A. Sousa-Junior (Author), Artur C. G. Silva (Author), Marize C. Valadares (Author), Andris F. Bakuzis (Author), Sebastião A. Mendanha (Author), Eliana M. Lima (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin (DOX) is a chemotherapeutic agent commonly used for the treatment of solid tumors. However, the cardiotoxicity associated with its prolonged use prevents further adherence and therapeutic efficacy. By encapsulating DOX within a PEGylated liposome, Doxil® considerably decreased DOX cardio...