Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties
Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the solid-state, both tautomers can be isolated as crystal forms A (1H-tautomer) and B (2...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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Elsevier,
2019-10-01T00:00:00Z.
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