Cathepsin-B inhibitor CA-074 attenuates retinopathy and optic neuritis in experimental autoimmune encephalomyelitis induced in SJL/J mice

• Main Authors: Mohammad Rashid Khan (Author), Sheikh Fayaz Ahmad (Author), Ahmed Nadeem (Author), Faisal Imam (Author), Naif O. Al-Harbi (Author), Mohd Shahnawaz Khan (Author), Meshal Alsahli (Author), Khaled Alhosaini (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The complicated multiple sclerosis (MS) can exhibit subacute sight deterioration and can lead to total deprivation of vision. In the current work, we explored the therapeutic outcome of Cathepsin B inhibitor (CA-074) against retinopathy and optic neuritis (ON) caused by experimental autoimmune encep...