Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects
Background: Wild edible plants (WEPs) including herbs provide staple foods as well as income for local communities on the African continent. However, these commonly used plant materials interact with orthodox or conventional drugs through both p-glycoprotein (P-gp) and cytochrome P450 enzymes inhibi...
Saved in:
Main Authors: | P.S. Kheoane (Author), K.C. Mokhetho (Author), S. Mokhele (Author), K.C. Mbara (Author), C.M. Leonard (Author), T.H. Gadaga (Author), C. Tarirai (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2025-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effect of genetic polymorphisms on the interplay of P-glycoprotein transporter and cytochrome P450 enzymes: Pharmacokinetics of risperidone
by: Yong-Bok Lee
Published: (2016) -
Effects of resveratrol on P-glycoprotein and cytochrome P450 3A in vitro and on pharmacokinetics of oral saquinavir in rats
by: Li JP, et al.
Published: (2016) -
Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein
by: Faisal Alotaibi
Published: (2023) -
Effects of duration of phenytoin administration on mRNA expression of cytochrome P450 and P-glycoprotein in the liver and small intestine of rats
by: Atsushi Kawase, et al.
Published: (2016) -
Physiologically‐Based Pharmacokinetic Modeling for the Prediction of a Drug-Drug Interaction of Combined Effects on P‐glycoprotein and Cytochrome P450 3A
by: Yukio Otsuka, et al.
Published: (2020)