CD73-Adenosine A1R Axis Regulates the Activation and Apoptosis of Hepatic Stellate Cells Through the PLC-IP3-Ca2+/DAG-PKC Signaling Pathway

• Main Authors: Zhenni Liu (Author), Xue Wu (Author), Qi Wang (Author), Zixuan Li (Author), Xueqi Liu (Author), Xiaodong Sheng (Author), Hong Zhu (Author), Mengda Zhang (Author), Junrui Xu (Author), Xiaowen Feng (Author), Baoming Wu (Author), Xiongwen Lv (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alcohol-related liver fibrosis (ALF) is a form of alcohol-related liver disease (ALD) that generally occurs in response to heavy long-term drinking. Ecto-5'-nucleotidase (NT5E), also known as CD73, is a cytomembrane protein linked to the cell membrane via a GPI anchor that regulates the convers...