Promoter hypermethylation patterns of P16, DAPK and MGMT in Oral Squamous Cell Carcinoma: A systematic review and meta-analysis

• Główni autorzy: K R Don (Autor), Pratibha Ramani (Autor), Vijayalakshmi Ramshankar (Autor), Herald Justin Sherlin (Autor), Priya Premkumar (Autor), Anuja Natesan (Autor)
• Format: Książka
• Wydane: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Oral squamous cell carcinoma (OSCC) is a common cancer world-wide that is highly lethal due to its recurrence and metastasis. Methylation is a common epigenetic mechanism that leads to gene silencing in tumors and could be a useful biomarker in OSCC. The prevalence of P16, death-associat...