Pharmaceutical Characterization of MyoNovin, a Novel Skeletal Muscle Regenerator: in silico, in vitro and in vivo Studies

• Main Authors: Samaa Alrushaid (Author), Neal M. Davies (Author), Judy E. Anderson (Author), Tyson Le (Author), Jaime A. Yáñez (Author), Zaid H. Maayah (Author), Ayman O.S. El-Kadi (Author), Ousama Rachid (Author), Casey L. Sayre (Author), Raimar Löbenberg (Author), Frank J. Burczynski (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PURPOSE: MyoNovin is a novel skeletal muscle-regenerating compound developed through synthesis of two nitro groups onto a guaifenesin backbone to deliver nitric oxide to skeletal muscle with a potential to treat muscle atrophy. The purpose of this study was to utilize in silico, in vitro, and in viv...