Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections

T2R bitter taste receptors in airway motile cilia increase ciliary beat frequency (CBF) and nitric oxide (NO) production. Polymorphisms in some T2Rs are linked to disease outcomes in chronic rhinosinusitis (CRS) and cystic fibrosis (CF). We examined the expression of cilia T2Rs during the differenti...

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Main Authors: Li Eon Kuek (Author), Derek B. McMahon (Author), Ray Z. Ma (Author), Zoey A. Miller (Author), Jennifer F. Jolivert (Author), Nithin D. Adappa (Author), James N. Palmer (Author), Robert J. Lee (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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