Pharmacokinetics/pharmacodynamics of glucocorticoids: modeling the glucocorticoid receptor dynamics and dose/response of commonly prescribed glucocorticoids

Background and purpose: The main features of the dynamics of the glucocorticoid receptor (GR) have been known for 50 years: 1) in the absence of glucocorticoid (G), the receptor is localized entirely in the cytoplasm; 2) upon G binding, GR is converted into a tightly bound G form and is rapidly impo...

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Bibliographic Details
Main Author: David Levitt (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2024-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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