Formulation and Preparation of Losartan-Potassium-Loaded Controlled-Release Matrices Using Ethocel Grade 10 to Establish a Correlation between In Vitro and In Vivo Results

• Main Authors: Kamran Ahmad Khan (Author), Ashfaq Ahmad (Author), Carlotta Marini (Author), Mario Nicotra (Author), Alessandro Di Cerbo (Author), Fazal- (Author), Naveed Ullah (Author), Gul Majid Khan (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the current study, matrices of losartan potassium were formulated with two different polymers (Ethocel 10 premium and Ethocel 10FP premium), along with a filler and a lubricant, at different drug-to-polymer <i>w</i>/<i>w</i> ratios (10:3, 10:4, and 10:5). The matrices were...