Effects of Coronavirus Disease 2019 (COVID-19) on Peripheral Blood Lymphocytes and Their Subsets in Children: Imbalanced CD4+/CD8+ T Cell Ratio and Disease Severity

• Main Authors: Shima Mahmoudi (Author), Bahareh Yaghmaei (Author), Meisam Sharifzadeh Ekbatani (Author), Babak Pourakbari (Author), Amene Navaeian (Author), Nima Parvaneh (Author), Mohammad Taghi Haghi Ashtiani (Author), Setareh Mamishi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: While pathogenesis in COVID-19 is not fully known and the effects between SARS-CoV-2 and the immune system are complicated, it is known that lymphopenia, hyper-inflammatory responses, and cytokines play an important role in the pathology of COVID-19. While some hematological abnormalit...