Pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GC-2 in rats. Part 1. Single and multiple intravascular and extravascular administration. Testing the hypothesis of linearity of pharmacokinetics

• Main Authors: O. Yu. Kravtsova (Author), O. G. Gribakina (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), P. O. Bochkov (Author), P. Yu. Povarnina (Author), V. P. Zherdev (Author)
• Formato: Livro
• Publicado em: LLC "Publisher OKI", 2023-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GC-2 in the rat blood plasma after different routes of administration was studied. The drug was administered at dose of 150 mg/kg by single and repeatedly. After single intravenous and intraperitoneal injection, GC-2 was detecte...