Generation of desminopathy in rats using CRISPR‐Cas9
Abstract Background Desminopathy is a clinically heterogeneous muscle disease caused by over 60 different mutations in desmin. The most common mutation with a clinical phenotype in humans is an exchange of arginine to proline at position 350 of desmin leading to p.R350P. We created the first CRISPR‐...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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Wiley,
2020-10-01T00:00:00Z.
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