Population Pharmacokinetic Analysis of Pazopanib in Patients and Determination of Target AUC

Population Pharmacokinetic Analysis of Pazopanib in Patients and Determination of Target AUC

Pazopanib is a potent multi-targeted kinase inhibitor approved for the treatment of advanced renal cell carcinoma and soft tissue sarcoma. The pharmacokinetics of pazopanib is characterized by a significant inter- and intra-patient variability and a target through plasma concentration of 20.5 mg·L&l...

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Main Authors: Agustos Cetin Ozbey (Author), David Combarel (Author), Vianney Poinsignon (Author), Christine Lovera (Author), Esma Saada (Author), Olivier Mir (Author), Angelo Paci (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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