Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea.

• Main Authors: Yohei Kurosaki (Author), N'Faly Magassouba (Author), Olamide K Oloniniyi (Author), Mahamoud S Cherif (Author), Saori Sakabe (Author), Ayato Takada (Author), Kenji Hirayama (Author), Jiro Yasuda (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Given the current absence of specific drugs or vaccines for Ebola virus disease (EVD), rapid, sensitive, and reliable diagnostic methods are required to stem the transmission chain of the disease. We have developed a rapid detection assay for Zaire ebolavirus based on reverse transcription-loop-medi...