Scaffold-Free Fabrication of Osteoinductive Cellular Constructs Using Mouse Gingiva-Derived Induced Pluripotent Stem Cells

• Main Authors: Hiroko Okawa (Author), Hiroki Kayashima (Author), Jun-Ichi Sasaki (Author), Jiro Miura (Author), Yuya Kamano (Author), Yukihiro Kosaka (Author), Satoshi Imazato (Author), Hirofumi Yatani (Author), Takuya Matsumoto (Author), Hiroshi Egusa (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Three-dimensional (3D) cell constructs are expected to provide osteoinductive materials to develop cell-based therapies for bone regeneration. The proliferation and spontaneous aggregation capability of induced pluripotent stem cells (iPSCs) thus prompted us to fabricate a scaffold-free iPSC constru...