Oxidative Stress in Transthyretin-Mediated Amyloidosis: An Exploratory Study

• Main Authors: Marco Fiore (Author), Chiara Cambieri (Author), Laura Libonati (Author), Federica Moret (Author), Edoardo D'Andrea (Author), Maria Grazia Di Certo (Author), Claudio Passananti (Author), Francesca Gabanella (Author), Nicoletta Corbi (Author), Matteo Garibaldi (Author), Cristina Chimenti (Author), Maria Alfarano (Author), Giampiero Ferraguti (Author), Silvia Francati (Author), Maurizio Inghilleri (Author), Marco Ceccanti (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transthyretin-mediated amyloidosis (ATTR) is a systemic disease with protein precipitation in many tissues, mainly the peripheral nerve and heart. Both genetic (ATTRv, "v" for variant) and wild-type (ATTRwt) forms are known. Beyond the steric encumbrance, precipitated transthyretin seems t...