Effect of inhaled air pollution particulate matter in alveolar macrophages on local pro-inflammatory cytokine and peripheral interferon γ production in response to Mycobacterium tuberculosis

• Main Authors: Yolanda Gonzalez (Author), Claudia Carranza (Author), Marco Iñiguez (Author), Martha Torres (Author), Raul Quintana (Author), Alvaro Osornio (Author), Carol Gardner (Author), Srijata Sarkar (Author), Stephan Schwander (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Human alveolar macrophages are first-line cellular responders to inhaled particulate matter (PM) and microbial pathogens in the lungs. We examined whether PM exposure affects human bronchoalveolar and peripheral blood mononuclear cell responses to Mycobacterium tuberculosis. Methods: Bro...