Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

• Main Authors: Matsumoto Hiroyuki (Author), Kurono Sadamu (Author), Shenoi Jaideep (Author), Rodgers Rosalie (Author), Kurien Biji T (Author), D'souza Anil (Author), Hensley Kenneth (Author), Nath Swapan K (Author), Scofield R Hal (Author)
• Format: Book
• Published: BMC, 2008-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Systemic lupus erythematosus (SLE) is a multifactorial disorder characterized by the presence of autoantibodies. We and others have implicated free radical mediated peroxidative damage in the pathogenesis of SLE. Since harmful free r...