Induction of Erythrocyte Membrane Blebbing by Methotrexate-Induced Oxidative Stress

• Main Authors: Tayyba Sattar (Author), Kashif Jilani (Author), Khalida Parveen (Author), Zahid Mushtaq (Author), Haq Nawaz (Author), Maham Abdul Bari Khan (Author)
• Format: Book
• Published: SAGE Publishing, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methotrexate (MTX) is a common chemotherapeutical agent and folate antagonist with reported apoptotic activity in nucleated cells. The presented research work was planned to investigate the eryptotic effects of methotrexate after the exposure of erythrocytes to therapeutical doses (10-15 μM) of meth...