The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice.

• मुख्य लेखकों: Chukwunonso Onyilagha (लेखक), Ping Jia (लेखक), Nipun Jayachandran (लेखक), Sen Hou (लेखक), Ifeoma Okwor (लेखक), Shiby Kuriakose (लेखक), Aaron Marshall (लेखक), Jude E Uzonna (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND:Bam32, a 32 kDa adaptor molecule, plays important role in B cell receptor signalling, T cell receptor signalling and antibody affinity maturation in germinal centres. Since antibodies against trypanosome variant surface glycoproteins (VSG) are critically important for control of parasitem...