The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice.

• Hoofdauteurs: Chukwunonso Onyilagha (Auteur), Ping Jia (Auteur), Nipun Jayachandran (Auteur), Sen Hou (Auteur), Ifeoma Okwor (Auteur), Shiby Kuriakose (Auteur), Aaron Marshall (Auteur), Jude E Uzonna (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

BACKGROUND:Bam32, a 32 kDa adaptor molecule, plays important role in B cell receptor signalling, T cell receptor signalling and antibody affinity maturation in germinal centres. Since antibodies against trypanosome variant surface glycoproteins (VSG) are critically important for control of parasitem...