Prostate cancer cell-derived exosomes ZNF667-AS1 reduces TGFBR1 mRNA stability to inhibit Treg expansion and DTX resistance by binding to U2AF1

• Main Authors: Zhenfeng Shi (Author), Wenjing Pu (Author), Min Li (Author), Mierzhayiti Aihemaitijiang (Author), Shuo Li (Author), Xiaoan Zhang (Author), Bide Liu (Author), Min Sun (Author), Jiuzhi Li (Author), Zhiwei Li (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Docetaxel (DTX) resistance attenuates anti-tumor effects of DTX on prostate cancer (mCRPC) and drug resistance was related to Treg expansion in tumors. ZNF667-AS1 played a suppressing role in various tumors and tumor-derived exosomes carry lncRNAs to participate in tumor progress...