A Protein-Based, Long-Acting HIV-1 Fusion Inhibitor with an Improved Pharmacokinetic Profile

• Үндсэн зохиолчид: Wei Xu (Зохиогч), Zhe Cong (Зохиогч), Qianyu Duan (Зохиогч), Qian Wang (Зохиогч), Shan Su (Зохиогч), Rui Wang (Зохиогч), Lu Lu (Зохиогч), Jing Xue (Зохиогч), Shibo Jiang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Recently, a series of highly effective peptide- or protein-based HIV fusion inhibitors have been identified. However, due to their short half-life, their clinical application is limited. Therefore, the development of long-acting HIV fusion inhibitors is urgently needed. Here, we designed and constru...