A Protein-Based, Long-Acting HIV-1 Fusion Inhibitor with an Improved Pharmacokinetic Profile

Recently, a series of highly effective peptide- or protein-based HIV fusion inhibitors have been identified. However, due to their short half-life, their clinical application is limited. Therefore, the development of long-acting HIV fusion inhibitors is urgently needed. Here, we designed and constru...

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Bibliographic Details
Main Authors: Wei Xu (Author), Zhe Cong (Author), Qianyu Duan (Author), Qian Wang (Author), Shan Su (Author), Rui Wang (Author), Lu Lu (Author), Jing Xue (Author), Shibo Jiang (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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