Postmitotic Expression of SOD1G93A Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation

• Asıl Yazarlar: Martina Martini (Yazar), Gabriella Dobrowolny (Yazar), Michela Aucello (Yazar), Antonio Musarò (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2015-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

To determine the role of mutant SOD1 gene (SOD1G93A) on muscle cell differentiation, we derived C2C12 muscle cell lines carrying a stably transfected SOD1G93A gene under the control of a myosin light chain (MLC) promoter-enhancer cassette. Expression of MLC/SOD1G93A in C2C12 cells resulted in dramat...