Postmitotic Expression of SOD1G93A Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation

To determine the role of mutant SOD1 gene (SOD1G93A) on muscle cell differentiation, we derived C2C12 muscle cell lines carrying a stably transfected SOD1G93A gene under the control of a myosin light chain (MLC) promoter-enhancer cassette. Expression of MLC/SOD1G93A in C2C12 cells resulted in dramat...

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Main Authors: Martina Martini (Author), Gabriella Dobrowolny (Author), Michela Aucello (Author), Antonio Musarò€ (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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