Effects of insulin-like growth factor-1 on the mRNA expression of estradiol receptors, steroidogenic enzymes, and steroid production in bovine follicles

• Main Authors: Ahmad Farid RAWAN (Author), Hikmatullah LANGAR (Author), Maho MUNETOMO (Author), Yuki YAMAMOTO (Author), Kohei KAWANO (Author), Koji KIMURA (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Insulin-like growth factor-1 (IGF-1) plays a crucial role in follicular growth and stimulates steroid hormone production in bovine follicles. Steroid hormones are synthesized through the actions of steroidogenic enzymes, specifically STAR, CYP11A1, HSD3B, and CYP19A1 in both theca cells (TCs) and gr...