Restoration of Polyamine Metabolic Patterns in In Vivo and In Vitro Model of Ischemic Stroke following Human Mesenchymal Stem Cell Treatment

• Main Authors: Tae Hwan Shin (Author), Geetika Phukan (Author), Jeom Soon Shim (Author), Duc-Toan Nguyen (Author), Yongman Kim (Author), Justin D. Oh-Lee (Author), Hyeon-Seong Lee (Author), Man Jeong Paik (Author), Gwang Lee (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated changes in PA levels by the treatment of human bone-marrow-derived mesenchymal stem cells (hBM-MSCs) in ischemic stroke in rat brain model and in cultured neuronal SH-SY5Y cells exposed to oxygen-glucose deprivation (OGD). In ischemic rat model, transient middle cerebral artery occlu...