Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria

• Main Authors: Seong-Cheol Park (Author), Hyosuk Son (Author), Young-Min Kim (Author), Jong-Kook Lee (Author), Soyoung Park (Author), Hye Song Lim (Author), Jung Ro Lee (Author), Mi-Kyeong Jang (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial peptides (AMPs) can combat drug-resistant bacteria with their unique membrane-disruptive mechanisms. This study aimed to investigate the antibacterial effects of several membrane-acting peptides with amphipathic structures and positional alterations of two tryptophan residues. The synt...