Folic Acid Attenuates Glial Activation in Neonatal Mice and Improves Adult Mood Disorders Through Epigenetic Regulation

• Main Authors: Tiantian Zhao (Author), Dong Wu (Author), Jingyi Du (Author), Guowei Liu (Author), Guangyu Ji (Author), Zixiao Wang (Author), Fan Peng (Author), Lajie Man (Author), Wenjuan Zhou (Author), Aijun Hao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Growing evidence indicates that postnatal immune activation (PIA) can adversely increase the lifetime risk for several neuropsychiatric disorders, including anxiety and depression, which involve the activation of glial cells and early neural developmental events. Several glia-targeted agents are req...