Long-term corticosteroid-induced chronic glaucoma model produced by intracameral injection of dexamethasone-loaded PLGA microspheres

• Main Authors: MJ Rodrigo (Author), D Garcia-Herranz (Author), A Aragón-Navas (Author), M Subias (Author), T Martinez-Rincón (Author), S Mendez-Martínez (Author), MJ Cardiel (Author), J García-Feijoo (Author), J Ruberte (Author), R Herrero-Vanrell (Author), L Pablo (Author), E Garcia-Martin (Author), I Bravo-Osuna (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose To evaluate a new chronic glaucoma model produced by intracameral injection of dexamethasone-loaded poly lactic-co-glycolic acid microspheres (Dex-PLGA-Ms) over six months. Methods Healthy rats received two injections (at baseline and Week 4) of Dex-PLGA-Ms into the anterior chamber of the r...