Emerging role of HJURP as a therapeutic target in cancers

• Main Authors: Jiaqi Tan (Author), Lertnimitphun Peeraphong (Author), Chattarin Ruchawapol (Author), Juan Zhang (Author), Juan Zhao (Author), Wenwei Fu (Author), Li Zhang (Author), Hongxi Xu (Author)
• Format: Book
• Published: Compuscript Ltd, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Holliday junction recognition protein (HJURP) is a key molecular chaperone for centromere protein A (CENP-A), which is essential for chromosome separation during mitosis and cell cycle regulation. Recent studies have identified the essential role of HJURP in carcinogenesis. Abnormal upregulation of...