Evolution and utility of preimplantation genetic testing for monogenic disorders in assisted reproduction - A narrative review

• Main Authors: Firuza R Parikh (Author), Arundhati S Athalye (Author), Dhananjaya K Kulkarni (Author), Rupesh R Sanap (Author), Suresh B Dhumal (Author), Dhanashree J Warang (Author), Dattatray J Naik (Author), Prochi F Madon (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a limited number of chromosomes, later called '...