Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study

• Main Authors: Muhammad Athar Abbasi (Author), Sajid Riaz (Author), Aziz- (Author), Sabahat Zahra Siddiqui (Author), Syed Adnan Ali Shah (Author), Muhammad Ashraf (Author), Muhammad Arif Lodhi (Author), Farman Ali Khan (Author)
• Format: Book
• Published: Universidade de São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presen...