BK_Ca Activator NS1619 Improves the Structure and Function of Skeletal Muscle Mitochondria in Duchenne Dystrophy

• Main Authors: Mikhail V. Dubinin (Author), Vlada S. Starinets (Author), Natalia V. Belosludtseva (Author), Irina B. Mikheeva (Author), Yuliya A. Chelyadnikova (Author), Anastasia D. Igoshkina (Author), Aliya B. Vafina (Author), Alexander A. Vedernikov (Author), Konstantin N. Belosludtsev (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Duchenne muscular dystrophy (DMD) is a progressive hereditary disease caused by the absence of the dystrophin protein. This is secondarily accompanied by a dysregulation of ion homeostasis, in which mitochondria play an important role. In the present work, we show that mitochondrial dysfunction in t...